Predictive value of foramen ovale size on pain recurrence after percutaneous balloon compression / 中南大学学报(医学版)

OBJECTIVES@#Primary trigeminal neuralgia (PTN) is a common cranial nerve disease in neurosurgery, which seriously endangers the physical and mental health of patients. Percutaneous balloon compression (PBC) has become an effective procedure for the treatment of PTN by blocking pain conduction through minimally invasive puncture. However, the recurrence of facial pain after PBC is still a major problem for PTN patients. Intraoperative balloon shape, pressure and compression time can affect the prognosis of patients with PBC after surgery. The foramen ovale size has an effect on the balloon pressure in Meckel's lumen. This study aims to analyse the predictive value of foramen ovale size for postoperative pain recurrence of PBC by exploring the relationship between foramen ovale size and postoperative pain recurrence of PBC.@*METHODS@#A retrospectively analysis was conducted on the clinical data of 60 patients with PTN who were treated with PBC in Department of Neurosurgery, Affiliated Hospital of Chengde Medical College from November 2018 to December 2021. We followed-up and recorded the Barrow Neurological Institute (BNI) pain score at 1, 3, 6 and 12 months after operation. According to the BNI pain score at 12 months after surgery, the patients were divided into a cure group (BNI pain score I to Ⅱ) and a recurrence group (BNI pain score Ⅲ to Ⅴ). The long diameter, transverse diameter and area of foramen ovale on the affected side and the healthy side of the 2 groups were measured. Receiver operating characteristic (ROC) curve and area under the curve (AUC) were used for analysis the relationship between the recurrence of pain and the long diameter, transverse diameter, area of foramen ovale on the affected side, and aspect ratio, transverse diameter ratio, area ratio of foramen ovale on the affected side to healthy side in the 2 groups.@*RESULTS@#At the end of 12 months of follow-up, 50 (83.3%) patients had pain relief (the cured group), 10 (16.7%) patients had different degrees of pain recurrence (the recurrence group), and the total effective rate was 83.3%. There were no significant differences in preoperative baseline data between the 2 groups (all P>0.05). The long diameter of foramen ovale on the affected side, the long diameter ratio and area ratio of foramen ovale on the affected/healthy side in the cured group were significantly higher than those in the recurrence group (all P<0.05), and there were no significant differences in the transverse diameter and area of foramen ovale on the affected side and the transverse diameter ratio of foramen ovale on the affected/healthy side between the 2 groups (all P>0.05). The ROC curve analysis showed that the AUC of the long diameter of foramen ovale on the affected side was 0.290 (95% CI 0.131 to 0.449, P=0.073), and the AUC of aspect ratio of foramen ovale on the affected side to healthy side was 0.792 (95% CI 0.628 to 0.956, P=0.004). The AUC of area ratio of foramen ovale on the affected side to healthy side was 0.766 (95% CI 0.591 to 0.941, P=0.008), indicating that aspect ratio and area ratio of foramen ovale on the affected side to healthy side had a good predictive effect on postoperative pain recurrence of PBC. When aspect ratio of foramen ovale on the affected side to healthy side was less than 0.886 3 or area ratio of foramen ovale on the affected side to healthy side was less than 0.869 4, postoperative pain recurrence was common.@*CONCLUSIONS@#Accurate evaluation of the foramen ovale size of skull base before operation is of great significance in predicting pain recurrence after PBC.

The ineffective or short-term recurrence of trigeminal neuralgia after microballoon compression:different causes and management strategies / 中华外科杂志

Objectives: To explore the causes of ineffective or short-term recurrence (within 3 months)of trigeminal neuralgia treated by percutaneous microballoon compression(PBC), and to examine the reoperative strategies and clincal outcomes of modified PBC. Methods: The clinical data of 21 patients with ineffective or short-term recurrence after PBC treatment (5.7% of 369 patient received PBC) admitted to the Department of Neurosurgery,Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University from June 2018 to June 2020 were retrospectively analyzed.There were 8 males and 13 females, mean aged 66.6 years (range:51 to 79 years).Among them,2 patients was ineffective after PBC and 19 patients relapsed within 3 months.The distribution of pain was along V2 branches in 2 cases,V3 branches in 3 cases,V1+V2 branches in 1 case,and V2+V3 branches in 15 cases.The mean time of recurrence was 46.8 days (range:23 to 76 days) among the 19 patients with short-term recurrence.The patients were divided into 4 types based on the causes of postoperative ineffectiveness or short-term recurrence.TypeⅠ:extracapsular false pear (1 case);Type Ⅱ:invalid true pear(2 cases);Type Ⅲ:capsular rupture (6 cases);Type Ⅳ:compression blind area (12 cases).The individualized modified PBC operation plans were used according to the types of the patients and the clinical effect and complications of the patients were observed. Results: The pain symptoms of the patients disappeared after the second operation with immediate effective rate of 100%. All patients had mild facial numbness after surgery.Five patients(23.8%,5/21) had masseter muscle weakness, 3 (14.3%,3/21) had peristomatous herpes, 1(4.8%, 1/21) had diplopia.No bleeding or other complications occurred.All patients were followed up for at least 12 months (range:13 to 28 months). One patient (4.8%,1/21) (compression blind area type) had pain recurrence 9 months after surgery, and cured by receiving the original modified PBC surgery again with no recurrence after another 13 months' follow-up. None of the other patients relapsed during the follow-up period.Up to the last follow-up,19 cases(90.5%,19/21) were cured,and 2 cases (9.5%,2/21) were relieved. Conclusions: The main reason for ineffective or short-term recurrence of PBC in trigeminal neuralgia patients is the ineffectively compressed of trigeminal ganglion.According to the different types of patients,the use of individualized modified surgical scheme can improve the efficacy of PBC surgery.

Internal Neurolysis (Nerve Combing) for Trigeminal Neuralgia without Neurovascular Compression

Objective The aim of the present study was to describe and evaluate the initial and the long-term clinical outcome of internal neurolysis (IN) for trigeminal neuralgia (TN) without neurovascular compression (NVC). Methods A total of 170 patients diagnosed with TN were treated by posterior fossa exploration, during the period between April 2012 and October 2019. The patients were divided into two groups: Group A (50 patients)was treated by IN and Group B (120 patients) received microvascular decompression (MVD). Surgical outcomes and postoperative complications were compared between the two groups. Pain intensity was assessed by the Barrow Neurological Institute (BNI) pain intensity score and BNI facial numbness score. Pain recurrence was statistically evaluated with Kaplan-Meier analysis. Results Pain was completely relieved in 44 patients (88%) who underwent IN (group A); 3 (6%) experienced occasional pain but did not require medication (BNI 2). In group B, 113 (94%) experienced immediate pain relief after MVD. The median duration of follow-ups was 4 years (6 months to 7.5 years). In Group A, there was a meantime recurrence of 27 months in 3 patients (6%). The recurrence in Group B was of 5.8% during the follow-up period. There were no statistically significant differences in the surgical outcomes between the two groups. All patients with IN experienced some degree of numbness, 88% of the cases resolved in 6 months, on average. Conclusion Internal neurolysis is an effective, safe and durable treatment option for trigeminal neuralgia when NVC is absent.

Trigeminal neuralgia recurrence: a comparison of microvascular decompression and percutaneous balloon compression: a five years follow-up study / Neuralgia do trigêmeo recorrente: uma comparação entre descompressão microvascular e compressão percutânea por balão: um estudo de acompanhamento de cinco anos

ABSTRACT Background: About 50% of patients that suffer from trigeminal neuralgia do not experience sustained benefit from the use of oral medication. For their adequate management, a few surgical procedures are available. Of these, percutaneous balloon compression (PBC) and microvascular decompression (MD) are two of the most performed worldwide. In this retrospective study, we present the outcomes of these techniques through estimation of initial pain relief and subsequent recurrence rate. Methods: Thirty-seven patients with medically refractory trigeminal pain surgically treated at Hospital Cajuru, Curitiba, Brazil, with PBC, MD or both between 2013 and 2018 were enrolled into this retrospective study. The post-procedural rate for pain relief and recurrence and associations between patient demographics and outcomes were analyzed. Results: MD had an earlier recurrence time than balloon compression. Of the 37 patients, the mean age was 61.6 years, approximately one third were male and most had type I neuralgia. The most affected branch was the maxillary (V2). The time for recurrence after surgery was on average 11.8 months for PBC and 9.0 months for MD. Complications were seen only with microsurgery. Conclusions: MD presented with a more precocious recurrence of pain than PBC in this article. Moreover, it had a higher recurrence rate than described in the literature as well, which is possibly explained by the type of graft (muscle) that was used to separate the neurovascular structures.

RESUMO Introdução: Cerca de 50% dos pacientes com neuralgia do trigêmeo não apresenta benefícios a longo prazo com o uso de medicação oral. Para a manutenção do tratamento, algumas opções cirúrgicas estão disponíveis, sendo a compressão percutânea por balão (CPB) e a descompressão microvascular (DM) algumas das modalidades mais realizadas em todo o mundo. Neste estudo retrospectivo, apresentamos os desfechos dessas técnicas por meio de estimativa da melhora inicial da dor e da taxa de recorrência subsequente. Métodos: Trinta e sete pacientes com dor trigeminal refratária ao tratamento medicamentoso tratados cirurgicamente no Hospital Cajuru, Curitiba, Brasil, com CPB, DM ou ambos entre 2013 e 2018 foram incluídos neste estudo retrospectivo. A taxa pós-procedimento para alívio e recorrência da dor e suas associações com a demografia e desfechos dos pacientes foram analisadas. Resultados: A DM foi associada a menor recorrência que a compressão por balão. Entre os 37 pacientes, a idade média foi de 61,6 anos, aproximadamente um terço eram do sexo masculino e a maioria apresentava neuralgia do tipo I. O ramo mais afetado foi o maxilar (V2). O tempo de recorrência após a cirurgia foi em média de 11,8 meses para CPB e 9,0 meses para DM. Foram vistas complicações apenas na microcirurgia. Conclusões: A DM apresentou recidiva mais precoce da dor em comparação à CPB. Além disso, apresentou uma taxa de recorrência mais alta do que a descrita na literatura, o que é possivelmente explicado pelo tipo de enxerto (músculo) usado para separar as estruturas neurovasculares.

Trigeminal Neuralgia Caused by Cerebellopontine Angle Tumors: Surgical Series

Introduction Cerebellopontine angle (CPA) tumors represent an important cause of persistent and refractory trigeminal neuralgia (TN). It is believed that between 1 and 9.9% of the cases of patients presenting with TN painful manifestation are caused by space-occupying lesions. Objective The objective of the present study is to describe the clinical and surgical experience of the operative management of patients presenting with secondary type TN associated with CPA tumors. Method An observational investigation was conducted with data collection from patients with secondary type TN associated with CPA tumors who were treated with surgical resection of the space-occupying lesion and decompression of the trigeminal nerve from January 2013 to November 2016 in 2 different centers in the western region of the state of São Paulo, Brazil. Results We operated on 11 consecutive cases in which TN was associated with CPA during the period of analysis. Seven (63.6%) patients were female, and 4 (36.4%) were male. Seven (63.6%) patients presented with right-side symptoms, and 4 (36.4%) presented with left-side symptoms. After 2 years of follow-up, we observed that 8 (72.7%) patients showed a complete improvement of the symptoms, with an excellent outcome, and that 3 (27.3%) patients showed an incomplete improvement, with a good outcome. No patient reported partial improvement or poor outcome after the follow-up. There was no operative mortality. Conclusion Cerebellopontine angle tumors represent an important cause of TNandmust be included in the differential diagnosis of patients presenting with refractory and persistent symptoms. Surgical treatment with total resection of the expansive lesion and effective decompression of the trigeminal nerve are essential steps to control the symptoms.

Abordaje asterional mínimamente invasivo para descompresión microvascular en neuralgia del trigémino / Minimally invasive asterional approach for microvascular decompression in trigeminal neuralgia

Resumen Objetivo: La neuralgia del trigémino (NT) es un trastorno neuropático susceptible de tratamiento quirúrgico. El objetivo es presentar los hallazgos quirúrgicos y resultados obtenidos en 26 pacientes con NT, tratados mediante un abordaje asterional mínimamente invasivo para descompresión vascular trigeminal. Métodos: Estudio longitudinal descriptivo. Se intervino mediante abordaje asterional a 26 pacientes. Se registró el historial médico, hallazgos quirúrgicos, respuesta al tratamiento y complicaciones. Se les dio seguimiento durante 36 meses. Resultados: Diecinueve casos se asociaron a compresión vascular, cinco casos a aracnoiditis y los dos restantes se relacionaron con esclerosis múltiple y neuralgia postherpética. El dolor se controló significativamente en todos los pacientes durante el postoperatorio inmediato. A 36 meses de seguimiento, en 25 pacientes se alcanzó un control total o aceptable del dolor. A largo plazo 22 pacientes evolucionaron sin complicaciones permanentes. Conclusiones: La cirugía de descompresión microvascular a través de un abordaje asterional mínimamente invasivo para el tratamiento de la NT es una alternativa con resultados similares al abordaje retrosigmoideo clásico, pero que suma las bondades de una técnica quirúrgica que se rige con los principios de la mínima invasión. Se requieren esfuerzos constantes para optimizar las técnicas quirúrgicas en el tratamiento de la NT.

Abstract Objective: Trigeminal neuralgia (TN) is a neuropathic disorder that can be treated surgically. This study aimed to present the surgical findings and the clinical outcomes of 26 patients with TN treated by minimally invasive asterional surgery. Methods: Longitudinal descriptive study. Twenty-six patients with TN underwent minimally invasive asterional surgery. The medical history, surgical findings, therapeutic response, and complications were registered. They were followed for 36 months. Results: Nineteen cases were associated with vascular compression; five were associated with arachnoiditis. The two remaining cases were associated with multiple sclerosis and post-herpetic neuralgia. The pain was substantially reduced in all patients in the immediate postoperative period. At 36 months, in 25 patients, total or acceptable pain control was achieved. In the long term, 22 patients evolved with no permanent complications. Conclusion: The microvascular decompression surgery by an asterional approach is an alternative with similar results to the classic retrosigmoid approach to treat TN, but that adds the benefits of the principles of minimally invasive surgery. Constant efforts need to be made to optimize minimally invasive surgical techniques for TN.

Alternative option for osteogenesis imperfecta and trigeminal neuralgia / Opção alternativa em tratamento da neuralgia do trigêmeo com osteogênese imperfeita

Summary Osteogenesis imperfecta (OI) is a bone disorder that can lead to skull base deformities such as basilar invagination, which can cause compression of cranial nerves, including the trigeminal nerve. Trigeminal neuralgia in such cases remains a challenge, given distorted anatomy and deformities. We present an alternative option, consisting in cannulation of the foramen ovale and classical percutaneous treatment. Percutaneous balloon microcompression was performed in a 28 year-old woman with OI and severe trigeminal neuralgia using computed tomography (CT) and radiographic-guided cannulation of the Gasserian ganglion without neuronavigation or stereotactic devices. The patient developed hypoesthesia on the left V1, V2 and V3 segments with good pain control. This alternative technique with a CT-guided puncture, using angiosuite without the need of any Mayfield clamp, neuronavigation systems, frame or frameless stereotactic devices can be a useful, safe and efficient alternative for patients with trigeminal neuralgia with other bone deforming diseases that severely affect the skull base.

Resumo Osteogênese imperfeita (OI) é uma doença óssea que pode levar a deformidades de base de crânio, como invaginação basilar que pode provocar compressão de nervo craniano, incluindo o nervo trigêmeo. Nestes casos, a neuralgia do trigêmeo permanece como um desafio, pela anatomia distorcida e pelas deformidades. Apresentamos uma alternativa que consiste na canulação do forame oval e no tratamento percutâneo clássico. A microcompressão percutânea por balão foi realizada em uma paciente de 28 anos apresentando OI e grave neuralgia do trigêmeo, sendo realizadas tomografia computadorizada (CT) e canulação guiadas do gânglio gasseriano sem neuronavegação ou dispositivos estereotáxicos. A paciente apresentou hipoestesia à esquerda dos segmentos V1, V2 e V3, com bom controle da dor. Essa técnica alternativa com punção orientada por CT utilizando o angiosuite sem a necessidade de qualquer grampo de Mayfield, sistemas de neuronavegação, ou dispositivos com ou sem arcos estereotáxicos, pode ser uma opção útil, segura e eficiente para pacientes com neuralgia do trigêmeo cursando com outras doenças deformativas que afetem a base craniana de modo grave.

Comparison of nerve combing and percutaneous radiofrequency thermocoagulation in the treatment for idiopathic trigeminal neuralgia / Comparação entre neurólise interna e termocoagulação percutânea por radiofrequência no tratamento da neuralgia idiopática do trigêmeo

ABSTRACT INTRODUCTION: Idiopathic trigeminal neuralgia (ITN) is a common pain disease in elderly people. Many methods have been used to alleviate the pain of patients, but few studies in the literature have compared the effect of nerve combing and percutaneous radiofrequency thermocoagulation. OBJECTIVE: The purpose of this study was to describe and evaluate the clinical outcome of idiopathic trigeminal neuralgia after nerve combing (NC) and compare them with those obtained using percutaneous radiofrequency thermocoagulation (RF). METHODS: The study included 105 idiopathic trigeminal neuralgia patients with similar symptom, age and underlying disease, which were divided into two groups. One group was treated by nerve combing (50 patients), the other by RF (55 cases). All patients were considered medical failures prior to the surgeries. A questionnaire was used to assess the long-term outcomes: pain relief, recurrence, complication and need for additional treatment. RESULTS: The median duration of follow-up in both groups was 90 months. Satisfactory relief was noted in 41 patients (82%), 5 patients (10%) initially experienced pain relief, then recurred, and four patients (8%) were designated poor among the group NC. In the group RF, satisfactory relief was noted in 42 patients (76.4%). There were eight "pain free with recurrence patients (14.5%) and 5 poor cases (9.1%). No statistically significant differences existed in the outcomes between both groups (p > 0.05). Postoperative morbidity included dysesthesia, diplopia, partial facial nerve palsy, hearing loss, tinnitus, cerebrospinal fluid leak, meningitis and mortality. CONCLUSION: Nerve combing and RF are both satisfactory treatment strategies for patients with ITN. Because of the higher risk of sensory morbidity and surgical risk as open surgery, RF is preferred as the recommended procedure for patients with ITN.

Resumo Introdução: A neuralgia idiopática do trigêmeo (NIT) é uma condição dolorosa comum em idosos. Muitos métodos têm sido usados para aliviar a dor dos pacientes, mas poucos estudos na literatura compararam o efeito de neurólise interna e termocoagulação percutânea por radiofrequência. Objetivo: O objetivo desse estudo foi descrever e avaliar o desfecho clínico de pacientes com neuralgia idiopática do trigêmeo após neurólise interna (NI) e compará-los com os obtidos usando termocoagulação percutânea por radiofrequência (RF). Método: O estudo incluiu 105 pacientes com NIT com sintomas, idade e doenças de base semelhantes, que foram divididos em dois grupos. Um grupo foi tratado por neurólise interna (50 pacientes) e o outro por RF (55 casos). Todos os pacientes haviam sido considerados fracassos terapêuticos antes das cirurgias. Um questionário foi utilizado para avaliar os resultados a longo prazo: alívio da dor, recorrência, complicações e necessidade de tratamento adicional. Resultados: A duração média do acompanhamento foi de 90 meses em ambos os grupos. Alívio satisfatório foi observado em 41 pacientes (82%); cinco pacientes (10%) experimentaram alívio inicial da dor, porém seguido de recrudescimento, e quatro pacientes (8%) apresentaram desfecho desfavorável no grupo NI. No grupo de RF, alívio satisfatório foi observado em 42 pacientes (76,4%). Houve oito pacientes livres de dor, com recorrência ''LDR'' (14,5%) e cinco casos com desfecho desfavorável (9,1%). Não houve diferenças significantes nos resultados entre os dois grupos (p > 0,05). Morbidade pós-operatória incluiu disestesia, diplopia, paralisia parcial do nervo facial, perda auditiva, tinnitus, fístula liquórica, meningite e óbito. Conclusão: Neurólise interna e RF são estratégias satisfatórias de tratamento para os pacientes com NIT. Em decorrência da maior morbidade sensorial e maior risco cirúrgico em uma cirurgia aberta, a RF é o procedimento mais indicado para pacientes com NIT.

Peripheral Neurectomy of Infraorbital Nerve -A Treatment Option for Trigeminal Neuralgia: A Case Report.

Trigeminal neuralgia or tic douloureux is a commonly diagnosed facial pain syndrome with a female predominance and with peak occurrence in the age group of above 50 years. Treatment options range from conservative pharmacologic therapy to invasive surgical procedures. The mode of treatment is based on patient’s systemic health, compliance and severity of the disease. Peripheral neurectomy is the safest and simplest method that can be accomplished under local anesthesia with minimum risks and excellent pain relief to the patient. However, there are incidences where this mode of treatment also fails to manage the disease, and further surgical options must be considered. In this case report, we present a case of a 50-year-old female patient who has undergone peripheral neurectomy of infraorbital nerve.

Microvascular decompression of the trigeminal nerve: technical note / Descompressão microvascular do nervo trigêmeo: nota técnica

The technique described by Jannetta uses Teflon ?turfs? (polytetrafluoroethylene). With the technological advancement of materials it is increasingly harder to find Teflon in the market. The author describes a technique which uses a portion of a vascular prosthesis made of polyester (FlowNit Bioseal®) manufactured by JOTEC® Gmbh reference 35BI1206. The use of this vascular prosthesis seems to be an effective alternative for intracranial neurovascular decompression. One of its advantages is having a circumferential format, which provides greater stability and safety to possible displacement.

A técnica descrita por Jannetta utiliza ?tufos? de Teflon (politetrafluoroetileno). Com o avanço tecnológico dos materiais, está cada vez mais difícil a aquisição de Teflon no mercado. O autor descreve uma técnica utilizando uma porção de prótese vascular de poliéster (FlowNit Bioseal®), fabricado por JOTEC® Gmbh referência 35BI1206. O uso da prótese vascular parece ser uma alternativa efetiva para descompressão neurovascular intracraniana. Possui a vantagem de apresentar o formato circunferencial, que permite maior estabilidade e segurança em possíveis deslocamentos.

Tratamiento neuroquirúrgico mínimamente invasivo de la neuralgia del trigémino: rizotomia percutánea con balón / Minimally invasive neurosurgical treatment of trigeminal neuralgia: percutaneous balloon Rhizotomy

Introducción: la neuralgia del trigémino esencial es una enfermedad en extremo invalidante, y si bien en sus primeras etapas el tratamiento farmacológico es eficaz, un porcentaje de pacientes se hacen refractarios. Es en estos casos en los que se plantea la opción de un tratamiento neuroquirúrgico. Material y método: se realiza un análisis retrospectivo de la casuística de pacientes a los cuales se les ha realizado una rizotomía trigeminal percutánea con balón en el Hospital Regional de Tacuarembó, en el Hospital Maciel, en el Hospital de Clínicas y en varios centros mutuales de Montevideo y del interior del país. En total se operaron 95 pacientes entre diciembre de 2004 y setiembre de 2010; 29 pacientes se operaron bajo neurolepto analgesia y 66 bajo anestesia general. Se utilizaron trócares específicos para la técnica y catéteres Fogarty® N° 4. En todos los casos se utilizó intensificador de imágenes para localizar el agujero oval. El promedio de internación en los casos no complicados fue de 48 horas. Resultados: 100 por ciento de los pacientes experimentaron un alivio completo del dolor en el período posoperatorio inmediato. El seguimiento ha sido entre dos meses y cinco años. En todos loscasos se suspendió la medicación en un plazo de tres a cuatro meses luego de la cirugía. De los pacientes operados entre 2004 y 2008, que constituye el subgrupo de enfermos con un seguimiento mínimo de dos años, el dolor recidivó en 16 por ciento de los casos. En un paciente (1 por ciento) se observaron complicaciones. No hubo mortalidad en esta serie. Conclusiones: la rizotomía percutánea con balón es una técnica muy segura, con excelente resultado en el alivio del dolor, permitiendo la suspensión del tratamiento farmacológico, que en muchos casos genera severos efectos colaterales, y que ofrece la posibilidad de ser repetidaen caso de recidiva con muy buena respuesta.

Introduction: essential trigeminal neuralgia is an extremely incapacitating disease, and, in spite of pharmacological treatment being effective in the first stages, a certain percentage of patients become refractory. In these cases, neurosurgical treatment is considered as a valid option. Method: a restrospective analysis of the casuistics was conducted for patients who were treated with percutaneous trigeminal rhizotomy in TacuarembóÆs Regional Hospital, in Hospital Maciel, in the University Hospital and in several private healthcare institutions in Montevideo, the capital city, and in the rest of the country. A total of 95 patients were operated from December 2004 through September 2010; 29 patients were operated under neuroleptic analgesia and 66 under general anesthesia. Technique-specific trocar needles and Fogarty® N° 4 catheters were used. In all cases, image intensifiers were used for the localization of the oval whole. Average hospital stay was 48 hours for non-complicated cases. Results: 100 percent of patients were completely relieved frompain in the immediate post-operative period. Follow-up ranged from two months to five years. In all cases, medication was suspended within three to four months after surgery. Out of the patients operated between 2004 and 2008, which correspond to the sub-group of patients whose follow-up lasted at least two years, pain recidivated in 16 percent of cases. One patient (1 percent) evidenced complications.There was no mortality in this group.Conclusions: percutaneous baloon rhizotomy is a very safe technique, and it is very effective to relieve pain, enabling the suspension of harmacological treatment, which in many cases results in severe side effects, and it is also possible to be repeated in the event of recidivism, achieving very good results.

Introdução: a nevralgia de trigêmeo essencial é uma doença invalidante, e embora o tratamento farmacológico seja eficaz em suas primeiras etapas, uma porcentagem de pacientes se tornam refratários. Nestes casos se sugere o tratamento neurocirúrgico como opção terapêutica. Material e método: realizou-se una análise retrospectiva da casuística de pacientes submetidos à rizotomia trigeminal percutânea com balão nos hospitais Regional de Tacuarembó, Maciel, Clínicas e em vários centros de atenção médica de Montevidéu e do interior do país. Foram operados 95 pacientes entre dezembro de 2004 e setembro de 2010; 29 pacientes foram operados com neuroleptoanalgesia e 66 com anestesia general. Foram utilizados trocartes específicos para a técnica e cateteres Fogarty® N° 4. Em todos os casos um intensificador de imagens para localizar o forâmen oval foi utilizado. O tempo médio de internação nos casos não complicados foi de 48 horas. Resultados: 100 por cento dos pacientes relataram alivio completo da dor no período pós-operatório imediato. O seguimento foi de dois meses a cinco anos. Em todos os casos se suspendeu a medicação depois de três a quatro meses da cirurgia. Considerando os pacientes operados entre 2004 e 2008, que constituem o subgrupo comseguimento mínimo de dois anos, a dor recidivou em 16 por cento dos casos. Um paciente (1 por cento) apresentou complicações.Não foram registrados óbitos nesta série. Conclusões: a rizotomia percutânea com balão é uma técnica segura, com excelente resultado para aliviar a dor, permitindo a suspensão do tratamento farmacológico, que em muitos casos gera efeitos colaterais graves, e oferece a possibilidade de ser repetida caso haja recidiva, com resposta muito boa.

Idiopathic trigeminal neuralgia: clinical presentations and operative findings on microvascular decompression

To analyze the clinical presentations of idiopathic trigeminal neuralgia and its operative findings on microvascular decompression. This descriptive case series study was conducted in the Department of Neurosurgery, PGML Govt. Lady Reading Hospital, Peshawar from July, 2003 to November, 2007. A total of 110 consecutive patients of idiopathic trigeminal neuralgia undergoing microvascular decompression in the Department of Neurosurgery, Lady Reading Hospital were included in the study. Clinical presentations and operative findings were recorded and analyzed. All cases of secondary trigeminal neuralgia were excluded with the help of MRI brain. Ratio of Male: female was 2:3. Age ranged from 28-80 years, mean age being 57 years. Right side was affected in 60% cases. Maxillary and mandibular divisions in combination were involved in majority of cases. Pain-free period varied from few hours to years. The common triggering stimuli were chewing and touching. A trigger point was found in [77%] cases. Superior cerebellar artery was the cause of compression in 90% of cases. In 90% of cases compression was on the root entry zone. The nerve compression was found on superomedial aspect in 66 [60%] of cases. Almost all cases of idiopathic trigeminal neuralgia are caused by a vascular compression of the trigeminal nerve, superior cerebellar artery being the commonest cause 90%

Tratamiento quirúrgico de la neuralgia del trigémino: Experiencia en 10 años / Surgical treatment of trigeminal neuralgia: A 10 years experience

Introduction. Surgical treatment of trigeminal neuralgia remains a matter of debate since there are no studies comparing long term effectiveness of the different surgical techniques. We present our 10 year experience. Description. Series: 40 patients. Period: 1998 - 2008. Surgical techniques: microvascular decompression, radiofrequency thermorhizotomy and balloon compression. Analyzed parameters: age, sex, nerve root involved, pain relief, recurrence, complications, need to restart medication and reintervention. Discussion. Microvascular decompression offers better long term results, radiofrequency is adequate for special cases (higher recurrence rate), and balloon compression is better for V1 neuralgia. Our sample is too small for statistics, yet our findings are coincident with the literature. Conclusion. Better patient selection criteria for each technique are needed. Microvascular decompression should be the treatment of choice when possible. How to treat recurrence remains unanswered.

Complications of MVD for trigeminal neuralgia

This standard approach describes the decompression of offending vessels at the root entry zone of 5th cranial nerve. We have operated upon 25 patients with different age group. C.T. Scan of all patients was normal except two. One had CP angle tumor and other had right epidermoid cyst. The aim of study was to evaluate the outcome and complication in one year follow up

Percutaneous radiofrequency rhizotomy and neurovascular decompression of the trigeminal nerve for the treatment of facial pain / Rizotomia percutânea por radiofreqüência e a descompressão neurovascular do nervo trigêmeo no tratamento das algias faciais

OBJECTIVE: To determine the outcomes of 354 radiofrequency rhizotomies and 21 neurovascular decompressions performed as treatment for 367 facial pain patients (290 idiopathic trigeminal neuralgia, 52 symptomatic trigeminal neuralgia, 16 atypical facial pain, 9 post-herpetic neuralgia). METHOD: Clinical findings and surgery success rate were considered for evaluation. A scale of success rate was determined to classify patients, which considered pain relief and functional/sensorial deficits. RESULTS: Radiofrequency rhizotomy was performed in 273 patients with idiopathic trigeminal neuralgia and in all other patients, except for trigeminal neuropathy; neurovascular decompression was performed in 18 idiopathic trigeminal neuralgia patients; 100 percent idiopathic trigeminal neuralgia, 96.2 percent symptomatic trigeminal neuralgia, 37.5 percent atypical facial pain and 88.9 percent post-herpetic neuralgia had pain relief. CONCLUSION: Both techniques for idiopathic trigeminal neuralgia are usefull. Radiofrequency rhizotomy was also efficient to treat symptomatic facial pain, and post-herpetic facial pain, but is not a good technique for atypical facial pain.

OBJETIVO: Determinar eficácia e achados pós-operatórios após 354 rizotomias por radiofreqüência e 21 descompressões neurovasculares como tratamento de 367 pacientes com dor facial (290 neuralgia idiopática do trigêmeo, 52 neuralgia sintomática do trigêmeo, 16 dor facial atípica, 9 neuralgia pós-herpética). MÉTODO: Achados clínicos e taxa de sucesso das cirurgias foram considerados para a avaliação. Uma escala avaliando alívio da dor e complicações sensoriais e funcionais foi utilizada para classificar os pacientes. RESULTADOS: A rizotomia por radiofreqüência foi realizada em 273 pacientes com neuralgia idiopática do trigêmeo e em todos os outros pacientes, exceto neuropatia trigeminal; descompressão neurovascular foi realizada em 18 pacientes com neuralgia idiopática do trigêmeo; 100 por cento dos pacientes com neuralgia idiopática do trigêmeo, 96.2 por cento dos pacientes com neuralgia sintomática, 37.5 por cento dos pacientes com dor facial atípica e 88.9 por cento dos doentes com neuralgia pós-herpética tiveram alívio da dor. CONCLUSÃO: Ambas as técnicas são úteis para a neuralgia idiopática do trigêmeo. A rizotomia por radiofreqüência foi também eficiente para tratar neuralgia sintomática do trigêmeo e pós-herpética, mas não foi uma boa técnica como tratamento da dor facial atípica.

Brain-stem auditory evoked responses during microvascular decompression for trigeminal neuralgia: predicting post-operative hearing loss.

CONTEXT: The importance of brainstem auditory evoked potential monitoring in reducing hearing loss during microvascular decompression for trigeminal neuralgia is now accepted. However the extent of the changes in the pattern of these potentials and the safe limits to which these changes are relevant in reducing postoperative hearing loss have not been established. AIMS: The aim of this study is to quantify these changes and relate these to the postoperative hearing loss. SETTINGS AND DESIGN: This study was done at the Walton Centre for neurology and neurosurgery, Liverpool, United Kingdom. The study was designed to give a measure of the change in the wave pattern following microvascular decompression and relate it to postoperative hearing loss. MATERIALS AND METHODS: Seventy-five patients undergoing microvascular decompression for trigeminal neuralgia had preoperative and postoperative hearing assessments and intraoperative brainstem auditory evoked potential monitoring. STATISTICAL ANALYSIS USED: Chi-square tests. RESULTS: It was found that the wave V latency was increased by more than 0.9 ms in nine patients, eight of whom suffered significant postoperative hearing loss as demonstrated by audiometry. It was also seen that progressive decrease in amplitude of wave V showed progressive hearing loss with 25% loss when amplitude fell by 50 and 100% loss when wave V was lost completely. However most of the patients did not have a clinically manifest hearing loss. CONCLUSIONS: A per-operative increase in the latency of wave V greater than 0.9 ms and a fall of amplitude of wave V of more than 50% indicates a risk to hearing.

Vertebrobasilar dolichoectasia as a cause of trigeminal neuralgia: the role of microvascular decompression. Case report

O objetivo desse estudo é relatar um caso de neuralgia trigeminal causado por dolicoectasia vertebrobasilar tratado com descompressão microvascular. Um homem (63 anos) consultou por neuralgia trigeminal recorrente na hemiface esquerda (territórios V2 e V3). A angiotomografia cerebral revelou compressão mecânica do nervo trigêmio esquerdo devido à dolicoectasia vertebrobasilar. O paciente foi submetido à craniotomia suboccipital esquerda. Introduziu-se Teflon® na área de conflito neurovascular, obtendo-se uma descompressão satisfatória. O paciente apresentou remissão da dor imediatamente. A dolicoectasia vertebrobasilar é uma causa rara de neuralgia trigeminal e uma excelente evolução pode ser alcançada com a descompressão microvascular.